Benefits of CBD for RLS – CBD for Restless Leg Syndrome

Benefits of CBD for RLS – CBD for Restless Leg Syndrome | EDO CBD

If you suffer from restless leg syndrome, you’re likely all-too-aware of the unpleasant RLS symptoms: tingling, burning sensations running along your legs when trying to get a good night’s sleep, coupled with the jolting urges to move your legs and neurological disorders.

Restless leg syndrome is the last thing anyone wants when they’re trying to rest, and it’s more common than one would think, affecting 1 out of every 10 Americans.

What is Restless Leg Syndrome and what are restless leg syndrome triggers? 

Restless leg syndrome, or Willis-Ekbom disease, is a neurological disorder that causes unpleasant sensations and a sense of hyperactivity in the legs of RLS patients, which are generally the most severe symptoms at night when the patient is sleeping or lying down.

As a condition that can cause both nighttime exhaustion and daytime sleepiness, RLS can greatly impact one’s mood, often affecting the individual’s productivity, memory, mood, and relationships.

Some cases of moderate to severe RLS are treated with an FDA-approved anti-seizure drug, gabapentin enacarbil, as well as opioids and benzodiazepines in the most extreme cases.

All About CBD

Taking CBD oil won’t get you high the way cannabis does, because it doesn’t contain its psychoactive counterpart, THC. THC triggers the dopamine rush associated with marijuana, and while CBD products contain traces of it, it’s not enough to create any effect.

When CBD enters our bodies, it interacts with the endocannabinoid system, which uses endocannabinoids to balance stress, sleep function, and sensations of pain. CBD oil encourages the endocannabinoid system to release more of its own cannabinoids, which efficiently help it calm nerves and dull pain receptor sensitivity–all without the high associated with the THC found in the cannabis plant.

Hemp derived CBD products are made from legal industrial hemp, which you can freely buy in any state without a prescription.

How Does CBD Work for RLS symptoms?

cbd for rls

As CBD has become more popular in recent years, there has been a growing amount studies done on how this chemical compound affects chronic pain, inflammation, and anxiety, as well as a surprising amount of research on how it impacts RLS and muscle pain.

Using CBD for RLS: CBD Dosage and Side Effects

The dosage for full spectrum CBD oil isn’t straightforward, so it’s always recommended to start with a low dosage. Individuals should consider body weight, tolerance levels, and the severity of RLS symptoms. It’s highly recommended to talk to a physician about the most suitable dosage. CBD Products containing 10-15 mg are suitable for most beginners.

There have been some side effects associated with CBD, including dry mouth, nausea, low blood pressure, and drowsiness. Broad spectrum CBD oil is not recommended for those taking any liver medication, as interaction may cause liver damage.

Full spectrum CBD has been used successfully to treat chronic muscle pain, anxiety, and inflammation in a safe way with no psychoactive side effects. CBD products have also been shown to be a promising treatment for RLS sufferers without the risk of addiction commonly associated with opioids.

That being said, marijuana derived CBD products have yet to receive FDA approval as a for RLS – CBD for Restless Leg Syndrome treatment, though they are widely available at health food stores and online.

Determining the Best CBD for restless legs syndrome

There are several ways you can take CBD for RLS symptoms and alleviate symptoms. While there are a few that will work better for this specific condition, it’s worth keeping your own preferences in mind as you consider them.

Sublingual CBD (i.e., tinctures)

Sublingual products tinctures applied below the tongue for 30 seconds to 1 minute without swallowing. Rather than digested, the CBD is delivered through the sublingual gland under your tongue

  • Bioavailability: 13-19% (some cases as high as 35%)
  • Delivers effects in approx. 20 minutes

If you are interested in trying a sublingual product for RLS, we recommend our 300 mg CBD Tincture, which is one of our best-selling products, and is perfect for those new to CBD.

Topical CBD (i.e., creams, balms, etc.)

People especially like to use CBD cream for restless leg syndrome because of the way it targets specific areas. Using CBD cream and lotion for restless legs is fast-acting. The CBD cream absorbs quickly through the skin to reach endocannabinoid receptors. 

  • Bioavailability: 6-20% (studies vary)
  • Delivers effects in approx. 30-120 minutes

If a topical cream is what suits your needs, we recommend our new CBD Pain Cream, which is formulated with turmeric, copaiba, and arnica.

CBD Cream for Pain

CBD Pain Cream


Intranasal CBD 

When vaped from a cartridge, CBD delivers the quickest supply of benefits. It provides a pleasant, nicotine-free experience in a variety of flavors.

  • Bioavailability: 34% to 46% (sometimes as high as 56%)
  • Delivers effects within 10 minutes

Edible CBD

Taking CBD in the form of gummies and other treats is an especially popular way to enjoy its benefits. They can be openly consumed without earning looks from passers-by. While CBD has a lower bioavailability, many consider this to be the most enjoyable experience.

  • Bioavailability: 6% to 20% 
  • Delivers effects within 20 minutes to 1 hour

If edibles strike your interest, our popular CBD Gummies are a must. These gummies deliver a delicious sweet and sour flavor and are 10 mg of CBD per gummy bear. 

60 Count


There is some evidence showing that CBD can improve mild symptoms related to RLS. While these claims aren’t entirely proven just yet, it’s encouraged to try it as a form of relieve RLS symptoms


What does the research say about CBD for restless legs syndrome?

Although Every Day Optimal is absolutely making no claims, this study conducted in Bordeaux, France found that 83% of its subjects experienced noticeable RLS syndrome relief. CBD for restless legs can effectively treat RLS and sleep disorders related to pain, such as apnea and RSL. An ongoing study on the effects of CBD on RLS is being conducted by an Israeli biotech company.

What is the best way to take CBD for restless legs syndrome?

You just dab a little CBD for restless legs on your skin and rub it in for a few minutes. CBD cream treats pain quickly by absorbing through the skin, targeting cannabinoid receptors upon entering the bloodstream.

Is CBD for restless legs syndrome an effective treatment?

While it might not be for everyone, CBD for restless legs syndrome is becoming a widely sought-out treatment, and maybe worth a discussion with your physician.

What can you do for restless legs at night?

RSL symptoms may be reduced by taking a warm bath before bed, avoid caffeine, and apply cool packs. Individuals who suffer from RSL may especially benefit from sleeping in a cool environment, so try turning down the thermostat. It is more effective to take CBD for restless legs syndrome.

How much CBD should I take for RLS?

CBD for restless legs dosages is tricky without the help of a medical expert, as it depends on the user’s weight, concerns, and the product itself. Simply starting out with a low dosage can help you determine how your body responds.

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