Benefits of CBD for RLS – CBD for Restless Leg Syndrome

cbd and restless leg syndrome

If you suffer from restless leg syndrome, you’re likely all-too-aware of the unpleasant symptoms: tingling, burning sensations running along your legs when trying to get a good night’s sleep, coupled with the jolting urges to move your legs.

Restless leg syndrome is the last thing anyone wants when they’re trying to rest, and it’s more common than one would think, affecting 1 out of every 10 Americans.

What is Restless Leg Syndrome? 

Restless leg syndrome, or Willis-Ekbom disease, is a disorder that causes unpleasant sensations and a sense of hyperactivity in the legs, which are generally most severe at night when the patient is sleeping or lying down.

As a condition that can cause both nighttime exhaustion and daytime sleepiness, RLS can greatly impact one’s mood, often affecting the individual’s productivity, memory, mood, and relationships.

Some cases of moderate to severe RLS are treated with an FDA-approved anti-seizure drug, gabapentin enacarbil, as well as opioids and benzodiazepines in the most extreme cases.

All About CBD

CBD won’t get you high the way cannabis does, because it doesn’t contain its psychoactive counterpart, THC. THC triggers the dopamine rush associated with marijuana, and while CBD products contain traces of it, it’s not enough to create any effect.

When CBD enters our bodies, it interacts with the endocannabinoid system, which uses endocannabinoids to balance stress, sleep function, and sensations of pain. CBD encourages the endocannabinoid system to release more of its own cannabinoids, which efficiently help it calm nerves and dull pain receptor sensitivity–all without the high associated with the THC found in cannabis.

Hemp-derived CBD is made from legal industrial hemp, which you can freely buy in any state without a prescription.

How Does CBD Work for Restless Leg Syndrome?

cbd for rls

As CBD has become more popular in recent years, there has been a growing amount studies done on how this chemical compound effects pain, inflammation, and anxiety, as well as a surprising amount of research on how it impacts RLS and muscle pain.

Using CBD for RLS: Dosage and Side Effects

The dosage for CBD isn’t straightforward, so it’s always recommended to start with a low dosage. Individuals should consider body weight, tolerance levels, and the severity of symptoms. It’s highly recommended to talk to a physician about the most suitable dosage. Products containing 10-15 mg are suitable for most beginners.

There have been some side effects associated with CBD, including dry mouth, nausea, low blood pressure, and drowsiness. CBD is not recommended for those taking any liver medication, as interaction may cause liver damage.

Determining the Best CBD for Restless Leg Syndrome

There are several ways you can take CBD for symptoms of RLS. While there are a few that will work better for this specific condition, it’s worth keeping your own preferences in mind as you consider them.

Sublingual CBD (i.e., tinctures)

Sublingual products tinctures applied below the tongue for 30 seconds to 1 minute without swallowing. Rather than digested, the CBD is delivered through the sublingual gland under your tongue

  • Bioavailability: 13-19% (some cases as high as 35%)
  • Delivers effects in approx. 20 minutes

If you are interested in trying a sublingual product for RLS, we recommend our 300 mg CBD Tincture, which is one of our best-selling products, and is perfect for those new to CBD.

Topical CBD (i.e., creams, balms, etc.)

People especially like to use CBD cream for restless leg syndrome because of the way it targets specific areas. Using CBD cream and lotion for restless legs is fast-acting. The CBD cream absorbs quickly through the skin to reach endocannabinoid receptors. 

  • Bioavailability: 6-20% (studies vary)
  • Delivers effects in approx. 30-120 minutes

If a topical cream is what suits your needs, we recommend our new CBD Pain Cream, which is formulated with turmeric, copaiba, and arnica.


CBD Cream for Pain

CBD Pain Cream


Intranasal CBD 

When vaped from a cartridge, CBD delivers the quickest supply of benefits. It provides a pleasant, nicotine-free experience in a variety of flavors.

  • Bioavailability: 34% to 46% (sometimes as high as 56%)
  • Delivers effects within 10 minutes

Edible CBD

Taking CBD in the form of gummies and other treats is an especially popular way to enjoy its benefits. They can be openly consumed without earning looks from passers-by. While CBD has a lower bioavailability, many consider this to be the most enjoyable experience.

  • Bioavailability: 6% to 20% 
  • Delivers effects within 20 minutes to 1 hour

If edibles strike your interest, our popular CBD Gummies are a must. These gummies deliver a delicious sweet and sour flavor and are 10 mg of CBD per gummy bear. 

60 Count


There is some evidence showing that CBD can improve symptoms related to RLS. While these claims aren’t entirely proven just yet, it’s encouraged to try it as a form of relief


What does research say about CBD oil for restless leg syndrome?

Although Every Day Optimal is absolutely making no claims, this study conducted in Bordeaux, France found that 83% of its subjects experienced noticeable RLS syndrome relief. 

Further, the Journal of Sleep Disorders and Therapy published a study suggested that cannabinoids can effectively treat sleep disorders related to pain, such as apnea and RSL.

 Meanwhile, an ongoing study on the effects of CBD on RLS is being conducted by an Israeli biotech company.

What is the best way to take CBD for RLS?

The best CBD method for each individual based on the desired bioavailability, as well as the individual’s preferences and needs, but CBD cream treats pain quickly by absorbing through the skin, targeting cannabinoid receptors upon entering the bloodstream. Topical CBD also tends to have a higher bioavailability, since it doesn’t have to be digested like capsules and edibles do.

Is CBD oil for restless legs syndrome an effective treatment?

As a growingly purported source of sleep and pain relief, CBD is gaining more research that may conclude its effectiveness.

While it might not be for everyone, CBD is becoming a widely sought-out treatment, and may be worth a discussion with your physician.

What can you do for restless legs at night?

Aside from whatever medication treatment you may or may not be using, RSL symptoms may be reduced some by taking a warm bath before bed, avoid caffeine, and apply cool packs or compresses. Individuals who suffer from RSL may especially benefit by sleeping in a cool environment, so try turning down the thermostat.

How much CBD should I take for RLS?

Dosages are tricky without the help of a medical expert, as it depends on the user’s weight, concerns, and the product itself. Simply starting out with a low dosage can help you determine how your body responds. 

Every Day Optimal Administrator
Every Day Optimal is a leading provider of cannabidiol products in the USA. We specialize in manufacturing top quality CBD oil products made from clean farmed, non-GMO, pesticide free hemp plants. We take great pride in producing the absolute best products you can find. If you have any questions, do not hesitate to reach out via chat, email or phone!
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Every Day Optimal Administrator
Every Day Optimal is a leading provider of cannabidiol products in the USA. We specialize in manufacturing top quality CBD oil products made from clean farmed, non-GMO, pesticide free hemp plants. We take great pride in producing the absolute best products you can find. If you have any questions, do not hesitate to reach out via chat, email or phone!

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